Clostridium difficile infection (CDI)
Challenge 2E
Clostridioides difficile infection (CDI)

Strategies to prevent and treat Clostridioides difficile infection (CDI) should be standardized by leadership to organize efforts on the frontline. Isolation of patients with CDI, rapid confirmation of CDI in patients, environmental cleaning precautions, and development of processes to prevent CDI should all be considered as fundamental components of a patient safety culture.

Executive summary checklist

Clostridioides difficile (also known as C.diff) is an opportunistic bacterium that can cause symptoms ranging from diarrhea to colitis or life-threatening inflammation of the colon (CDC,2012). C. diff is a spore-forming, Gram-positive anaerobic bacillus bacteria that produces two exotoxins: toxin A and toxin B (CDC, 2012). Transmission of C. diff is

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