Actionable Patient Safety Solutions (APSS)

23A Early Detection and Treatment of Sepsis

The Sepsis APSS Blueprint outlines actionable steps healthcare organizations should take to successfully implement and sustain improvements in order to reduce sepsis morbidity and mortality. Actionable steps to improve sepsis rates and summaries of available evidence-based practice protocols are included:

  • Leadership checklist guide to determine whether current evidence-based guidelines are being followed in your organization
  • Performance improvement plan to follow if improvements are necessary
  • Clinical workflow for sepsis early detection and recognition across the continuum
  • Knowledge base on early detection and treatment of sepsis
  • How to educate patients and family members about sepsis prevention, recognition, and treatment and recognition of post-sepsis syndrome after discharge
  • Sepsis resource guide
  • Guidance on how to measure outcomes

The Blueprint is revised annually and is available free of charge on our website.

Hospitals that make a formal commitment to improve sepsis and share their successes on the PSMF website have access to an additional level of consulting services.

Executive summary

The Problem Any infection can lead to sepsis and worldwide, one-third of people who develop sepsis die (Sepsis Alliance, 2019). Mortality from sepsis increases by as much as 8% for every hour that treatment is delayed. As many as 80% of sepsis deaths could be prevented with standardization and mobilization of

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